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Volume: 3

Voice Flows To And Around Leaders: Understanding When Units Are Helped Or Hurt By Employee Voice

In two studies, we develop and test theory about the relationship between speaking up, one type of organizational citizenship behavior, and unit performance by accounting for where employee voice is flowing. Results from a qualitative study of managers and professionals across a variety of industries suggest that voice to targets at different formal power levels (peers or superiors) and locations in the organization (inside or outside a focal unit) differs systematically in terms of its usefulness in generating actions to a unit's benefit on the issues raised and in the likely information value of the ideas expressed. We then theorize how distinct voice flows should be differentially related to unit performance based on these core characteristics and test our hypotheses using time-lagged field data from 801 employees and their managers in 93 units across nine North American credit unions. Results demonstrate that voice flows are positively related to a unit's effectiveness when they are targeted at the focal leader of that unitwho should be able to take actionwhether from that leader's own subordinates or those in other units, and negatively related to a unit's effectiveness when they are targeted at coworkers who have little power to effect change. Together, these studies provide a structural framework for studying the nature and impact of multiple voice flows, some along formal reporting lines and others that reflect the informal communication structure within organizations. This research demonstrates that understanding the potential performance benefits and costs of voice for leaders and their units requires attention to the structure and complexity of multiple voice flows rather than to an undifferentiated amount of voice.Business Administratio

In-beam Tests of a Ring Imaging Cerenkov Detector With a Multianode Photomultiplier Readout

A ring-imaging \v{C}erenkov counter read out by a 100-channel PMT of active area 10$\times$10 cm$^2$ was operated successfully in a test beam at the BNL AGS with several radiator gases, including the heavy fluorocarbon C$_4$F$_{10}$. Ring radii were measured for electrons, muons, pions and kaons over the particle momentum range from 2 to 12 GeV/$c$, and a best resolution of $\sigma_r/r = 2.3\%$ was obtained.Comment: 11 pages (LaTeX) plus 7 figures in Postscript (gz-compressed and uuencoded

Cell wall arabinan is essential for guard cell function

Stomatal guard cells play a key role in the ability of plants to survive on dry land, because their movements regulate the exchange of gases and water vapor between the external environment and the interior of the plant. The walls of these cells are exceptionally strong and must undergo large and reversible deformation during stomatal opening and closing. The molecular basis of the unique strength and flexibility of guard cell walls is unknown. We show that degradation of cell wall arabinan prevents either stomatal opening or closing. This locking of guard cell wall movements can be reversed if homogalacturonan is subsequently removed from the wall. We suggest that arabinans maintain flexibility in the cell wall by preventing homogalacturonan polymers from forming tight associations

"The Practical Perforator Flap": the sural artery flap for lower extremity soft tissue reconstruction in wounds of war

Background: Sural artery perforator flaps have been described for use as both local flaps and in free tissue transfer. We present the use of this flap for compound soft tissue defects of the lower limb in civilian casualties of armed conflict in Afghanistan. Methods/results: Detailed description of the management of blast and high-velocity projectile wounds of the lower extremity with the use of local sural perforator flaps and a review of literature. Conclusions: Sural artery perforator flaps may be harvested to cover complex lower limb defects. The use of this technique is not limited

Measurement of Forward Jets Produced in High-Transverse-Momentum Hadron-Proton Collisions

A measurement of charged-particle production is reported for the forward region in events triggered by high-transverse-momentum (p⊥) jets and single particles. The momentum distributions of forward-going particles are observed to scale in a simple p⊥-dependent longitudinal variable. Forward-going (beam) jets are observed to be tilted away from the original direction by an amount which agrees with muon-pair data when interpreted in a parton (quantum-chromodynamics) model

Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour.

AIMS/HYPOTHESIS: Hypothalamic glucose-excited (GE) neurons contribute to whole-body glucose homeostasis and participate in the detection of hypoglycaemia. This system appears defective in type 1 diabetes, in which hypoglycaemia commonly occurs. Unfortunately, it is at present unclear which molecular components required for glucose sensing are produced in individual neurons and how these are functionally linked. We used the GT1-7 mouse hypothalamic cell line to address these issues. METHODS: Electrophysiological recordings, coupled with measurements of gene expression and protein levels and activity, were made from unmodified GT1-7 cells and cells in which AMP-activated protein kinase (AMPK) catalytic subunit gene expression and activity were reduced. RESULTS: Hypothalamic GT1-7 neurons express the genes encoding glucokinase and ATP-sensitive K(+) channel (K(ATP)) subunits K ( ir ) 6.2 and Sur1 and exhibit GE-type glucose-sensing behaviour. Lowered extracellular glucose concentration hyperpolarised the cells in a concentration-dependent manner, an outcome that was reversed by tolbutamide. Inhibition of glucose uptake or metabolism hyperpolarised cells, showing that energy metabolism is required to maintain their resting membrane potential. Short hairpin (sh)RNA directed to Ampkα2 (also known as Prkaa2) reduced GT1-7 cell AMPKα2, but not AMPKα1, activity and lowered the threshold for hypoglycaemia-induced hyperpolarisation. shAmpkα1 (also known as Prkaa1) had no effect on glucose-sensing or AMPKα2 activity. Decreased uncoupling protein 2 (Ucp2) mRNA was detected in AMPKα2-reduced cells, suggesting that AMPKα2 regulates UCP2 levels. CONCLUSIONS/INTERPRETATION: We have demonstrated that GT1-7 cells closely mimic GE neuron glucose-sensing behaviour, and reducing AMPKα2 blunts their responsiveness to hypoglycaemic challenge, possibly by altering UCP2 activity. These results show that suppression of AMPKα2 activity inhibits normal glucose-sensing behaviour and may contribute to defective detection of hypoglycaemia.This study was funded by: grants from the Wellcome Trust (grant numbers 068692 and 086989) and Diabetes UK (grant number RD08/0003681) to M.L.J. Ashford; a Juvenile Diabetes Research Foundation (JDRF) Postdoctoral Fellowship to C. Beall (grant number 3-576-2010); grants from JDRF and European Foundation for the study of Diabetes to R.J. McCrimmon, and from the British Heart Foundation to A. Jovanović

Jets Produced in π^-, π^+, and Proton Interactions at 200 GeV on Hydrogen and Aluminum Targets

This paper presents results from an experiment on the production of jets (groups of particles) with high p_⊥ produced in 200-GeV/c interactions. Results are presented on the comparison of jet cross sections on aluminum and hydrogen targets. The jet fragmentation distributions are also examined. Both the cross section and the jet structure are found to depend strongly on the beam and target types

Observation of the Production of Jets of Particles at High Transverse Momentum and Comparison with Inclusive Single-Particle Reactions

Data are presented on production by 200-GeV/c hadrons incident on beryllium of both single particles and jets (groups of particles) with high p_T (transverse momentum). The experiment was performed in a wide-aperture multiparticle spectrometer at Fermilab. The jet and single-particle cross sections have a similar shape from p_T=3 to 5 GeV/c but the jet cross section is over two orders of magnitude larger. The distributions of charged-particle momenta show striking similarities to those observed in lepton-induced processes

Experimental Tests of Quantum Chromodynamics in High-p_⊥ Jet Production in 200-GeV/c Hadron-Proton Collisions

Data on inclusive jet production in the transverse-momentum (p_⊥) range 0-8 GeV/c for 200-GeV/c p, π^-, π^+, K^-, K^+, and p incident on a hydrogen target are presented. The jet cross section is fully corrected for losses and biases, and compared with the predictions of a model based on quantum chromodynamics. Both the absolute cross section and the inclusive charged-particle distributions inside and outside the jet are in qualitative agreement with the model